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Pregnancy Insulin Resistance and Subsequent Gestational Diabetes Mellitus

In order to study the relationship between insulin resistance (IR) and gestational diabetes mellitus (GDM), Woman's Health Research Institute is conducting a study to validate a convenient and sensitive measurement of insulin resistance and beta-cell function in pregnant African-American women and Caucasian women who are at risk for gestational diabetes mellitus. We will further examine whether there are differences in IR, which vary by race in our patient population, which may result in new strategies for the clinical screening and management of pregnant women at Woman's Hospital.

This study is open to African-American and Caucasian women between 18-42 years of age who are 20-30 weeks of gestation and whose physician has ordered a 3-hr oral glucose tolerance test. Patients who wish to participate in the study cannot be currently taking medication known to influence carbohydrate metabolism or have known diabetes mellitus, liver, heart, lung, or kidney disease.

In addition to the blood samples that are drawn for a standard 3-hr glucose tolerance test, patients who consent to the study will have a single additional tube of blood drawn at 30 minutes for measurement of insulin and glucose and extra blood withdrawn for insulin determinations at all other standard time points. This study does not require the physician to order the additional tests, which will be provided at no cost to the patient. Patients must consent for the study prior to the first blood draw of their glucose tolerance test to participate. All the laboratory results will be provided to the physician along with the ordered glucose values. Physicians will receive the standard glucose tolerance interpretations from the 3-hr OGTT. Interpretation of the insulin secretory function will be provided at completion of the study.

If you are interested in participating please contact Woman's Health Research Institute at 225-231-5275. Please complete and submit this screening form to help us determine if you qualify to participate in the research study.

First Name*:
Last Name*:
Middle Initial*:
Address 1*:
Address 2:
City*:
State*:
Zip*:
Country*:
Home Phone Number*:
Work Phone Number*:
Cellphone Number*:
Date of Birth*:
Email Address*:
Physician's Name*:

Please check items that apply to you.
Race	Caucasian African American Other
Do you have a history of Diabetes?
Do you have a history of liver diseases?
Do you have a history of heart diseases?
Do you have a history of kidney diseases?
Do you have a history of lung diseases?
Are you currently taking any medications that are known to interfere with glucose or insulin metabolism?	Yes No Not Sure
Due Date*: